
产品货号:
Z18002
中文名称:
HLA-DQB1抗体
英文名称:
Anti-HLA-DQB1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HLA-DQB1 Antibody |
指标别名 | major histocompatibility complex;class II;DQ beta 1;CELIAC1;HLA-DQB;IDDM1;HLA-DQB1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,ICC/IF |
基因名称 | HLA-DQB1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence of human HLA-DQB1 (DAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR). |
实际分子量 | 30KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Major histocompatibility complex,class II,DQ beta 1,also known as HLA-DQB1,is a human gene and also denotes the genetic locus that contains this gene.HLA-DQB1 belongs to the HLA class II beta chain paralogs.This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB),both anchored in the membrane.It plays a central role in the immune system by presenting peptides derived from extracellular proteins.Class II molecules are expressed in antigen presenting cells (APC:B lymphocytes,dendritic cells,macrophages).The beta chain is approximately 26~28kDa and it contains six exons.Exon 1 encodes the leader peptide,exons 2 and 3 encode the two extracellular domains,exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities,resulting in up to four different molecules.Typing for these polymorphisms is routinely done for bone marrow transplantation.Alternative splicing results in multiple transcript variants. |
Uniprot ID | P01920 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 |
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